Past Studies

The Hope Clinic has successfully completed recruitment in a number of vaccine studies related to HIV, HPV, influenza, yellow fever, and even Ebola. See below for some of these.

HVTN Studies in Follow Up

HVTN 910 A clinical trial to assess the persistence of HIV vaccine-induced seropositivity (VISP) in participants who received a vaccine in a DAIDS funded preventive HIV vaccine trial. This study allows HIV-negative participants to have two HIV tests per year until they have three consecutive test results that show no vaccine-induced antibodies to HIV.

HVTN 117 The purpose of this study is to assess the safety/tolerability of the 2 different vaccine regimens of priming with trivalent Ad26.Mos.HIV and boosting with trivalent Ad26.Mos.HIV and Clade C gp140 plus adjuvant or priming with tetravalent Ad26.Mos4.HIV and boosting with Ad26.Mos4.HIV and Clade C glycoprotein (gp)140 plus adjuvant. Immune responses of the different vaccine schedules will be assessed.

Janssen Study 118 A clinical research study being conducted to determine the safety and effectiveness of an investigational vaccine for the prevention of HIV. 

HVTN 119 (HIV Vaccine Clinical Trials Network) A clinical research study being conducted in Atlanta to determine the safety and effectiveness of an investigational vaccine for the prevention of HIV. You may qualify if you are a healthy adult between the ages of 22 - 50 and are HIV negative. Compensation is provided to volunteers for their time and travel. 

HVTN 120 (HIV Vaccine Clinical Trials Network)  A clinical research study in Atlanta to evaluate the safety and tolerability of an experimental HIV vaccine. 

HVTN 124 A clinical trial research study investigating 2 experimental vaccines against HIV. One of them is a DNA vaccine. The DNA in the vaccine tells the body to make 5 proteins that are similar to proteins from HIV. The second vaccine is a protein vaccine. The vaccine is made of 4 man-made proteins that match 4 of the proteins the body makes from the DNA vaccine. In this study, the protein vaccine also includes an adjuvant called GLA-SE. An adjuvant is a substance used to increase the body’s responses to a vaccine.

Closed Studies

  • HVTN 098 
  • HVTN 110
  • HVTN 505

HPTN Studies in Follow-Up

Amp Study The Antibody-Mediated Study (Closed) is a clinical trial research study to investigate the usefulness of an antibody to prevent HIV among non-HIV infected adults at risk of HIV-infection. 

083 (Infiniti) The infinity study evaluates whether Cabotegravir (CAB), an investigational new drug is as safe and works as well as FDA-Approved Truvada (Pre-exposure prophylaxis or PrEP) in protecting individuals with high sexual exposure from acquiring HIV.  PrEP is an anti-HIV medication taken once daily that keeps HIV negative people from becoming infected with HIV.

Norovirus Study is a research study in Atlanta being done to determine the safety and tolerability of the Snow Mountain Virus (SMV) and the number of norovirus particles needed to make a person sick. We are looking for healthy adults, 18-49, who are willing and available to be in the hospital for 5 days. Noroviruses are the most common cause of gastroenteritis (stomach flu). You will be hospitalized for 5 days and have 4 follow-up visits and one phone call at 6 months. 

H7N9 study involves 2 H7N9 vaccination visits. You may be eligible if you are a healthy adult 19 or older, live in the greater Atlanta area, and are available for 7 clinic visits and 5 telephone calls over 13 months. 

VAX2 004 A Chicken Pox Vaccine Immunology clinical research study recruiting volunteers in the greater Atlanta area. We are looking for healthy volunteers over the age of 18 with proof of prior chickenpox vaccination. The study involves 1 to 2 clinic visits, blood draw, and an optional bone marrow aspiration. 

Zika Natural History Study A clinical trial research study in Atlanta to better understand the effects of the Zika virus on the body. This information can be used to help develop a vaccine as well as better diagnostic and therapeutic tools in the future. No treatment or drugs will be given in this study. 

CDiff study The Cdiffense Clostridium Difficile Vaccine Trial (closed) is a clinical trial research study to investigate a vaccine against the clostridium difficile "C. diff" among adults age 50 years or order. C Diff is a disease common among recently hospitalized individuals, particularly those of older age. 

Micro Biome Study A new clinical trial research study in need of volunteers who are willing to donate a stool sample. 

Influenza Heavy Water Study  A clinical trial research study to investigate the immune responses to the seasonal flu vaccine and to track the responses using special water called heavy water. Participants must be between the ages of 18-45 and can not have had the flu shot in the past three years. 

Respiratory Syncytial Virus (RSV) Study
The Hope Clinic is working on a research study to see how common viral infections are in those ≥50 years of age. We need healthy adults ≥ 50 years of age to help us learn more about RSV, and help us determine if adults could benefit from a vaccine.

VRC 313 The VRC 313 study is seeking to determine if an experimental encephalitis vaccine is safe and if there are any side effects.  The vaccine will be given as a shot in the arm.